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Research shows that restoring robust GLP-1 signaling can reduce appetite by 20-30% and support sustainable weight loss

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PMID 20353808

Compared with untreated individuals, those receiving GLP-1 therapy showed lower levels of pro-inflammatory cytokines (IL-6, TNF-, IL-12), higher levels of IL-10, reduced expression of endothelial adhesion molecules (ICAM-1, VCAM-1), and decreased leukocyte rolling and adhesion along the vascular endothelium [15]