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Interestingly, supplementation of metformin with 1.5 mg dulaglutide per week in the treatment of T2MD in obese patients with severe impairment of glycosylated hemoglobin A1c (HbA1c) was reported to bring lasting benefits in the control of glucose metabolism and body weight (173)

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Studies in humans and animals have shown that proteins/peptides in the diet will help to stimulate the secretion of GLP-1 and that dietary amino acids, peptides, and phytochemicals (quercetin), can all stimulate GLP-1 secretion