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At pharmacological doses, ipamorelin does not measurably raise cortisol, prolactin, or ACTH in rat pituitary cell studies [2]

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From 2008-2010, Sanofi-Aventis Acomplia (selective CB1 antagonist) and Abbott Laboratories Meridia (NE/5-HT reuptake inhibitor)--both also designed to suppress appetite--were pulled from the market over similar cardiac safety concerns

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