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Consistent reduction in major cardiovascular events, even beyond glycaemic effects Meaningful kidney protection, slower eGFR decline & reduced albuminuria Benefits across phenotypes: diabetes, obesity, HFpEF, CKD & ASCVD A clear shift from organ-specific treatment to system-level risk reduction The next phase feels less about whether these agents work & more about who benefits most, when to start & how to integrate them alongside SGLT2 inhibitors and standard CV therapies

Individuals who have tried dieting and exercise alone without seeing the results they want may also benefit from the enhanced metabolic support

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If you are considering glutathione IV therapy, professional guidance will help you understand what results to expect

Patients with significant dyslipidaemia require appropriate lipid-lowering therapy according to NICE guideline NG238