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Statistical evaluation of the data was carried out using an unpaired t-test (plasma analytes in study 1, in vitro data), paired t-test (plasma linagliptin), two-way analysis of variance (ANOVA) with Dunnetts post-hoc test (body weight, food intake, OGTT), or KruskalWallis test (plasma analytes in study 2)
The main peptidereceptor interactions identified in the MD are summarised in Fig
PMID: 70 ClarkeLPassamRTFalaheeBJirapinyoPAllegrettiJRKellyCR
Diabetes Obes Metab 17:268275
As GSH: GSSG serves as an accurate representation of cellular redox status it is also valuable as a biomarker for patient classification, active monitoring of treatment and the patients physiologic response, and an easily obtained measure of immune exhaustion or oxidative burden (Rossi et al., 2006
