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Key properties: Stimulates GH release from the pituitary (not the hypothalamus) Does not significantly raise cortisol or prolactin Short half-life (~2 hours) produces a sharp, pulsatile GH release Does not block somatostatin (the hormone that inhibits GH release) Selective for GH minimal effect on other hormones The selectivity is what makes ipamorelin the preferred GHRP for most protocols

Choose one that includes iron, zinc, selenium, and B vitamins

GLP-1 medications are often placed on higher formulary tiers, resulting in higher cost-sharing

References Giles A, Foushee J, Lantz E, Gumina G

Remember not to inject in the same spot twice in a row