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Currently approved GLP-1 treatments in the UK include injectable semaglutide (Wegovy) and liraglutide (Saxenda), available through specialist NHS services

doi:10.1016/j.ghir.2009.03.001 (source) Henninge J, Pepaj M, Hullstein I, Hemmersbach P

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Bath application of GLP-1 induces a depolarization in most hippocampal neurons and a hyperpolarization in a few neurons ( in vitro electrophysiological recordings further demonstrated that exendin-4 elicits an early fast excitatory response dose-dependently (Hsu et al., 2015, 2018)

These compounds have been shown in animal studies to improve insulin sensitivity and reduce inflammation, making them a notable subject of current metabolic research