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These changes reduce its binding affinity to IGF-binding proteins (IGFBPs), allowing for a longer half-life (up to 2030 hours) and increased bioavailability in plasma
Theory and practice of histological techniques
10.1158/1078-0432.CCR-12-2334 105 HassaneinM.QianJ.HoeksemaM
Dehydration increases heart rate because the heart must beat faster to maintain blood pressure with reduced blood volume
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