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2.4 Metabolic and mitochondrial dysfunction in diabetes An animal experiment using db/db mice, a model of type 2 diabetes, demonstrated that disturbances in circulatory metabolism and brain energy metabolism, particularly mitochondrial dysfunction, may contribute to cognitive impairment

The disease is also known as chronic lymphocytic thyroiditis or autoimmune thyroiditis

There are two big problems with this

Activated NK cells rely on enhanced glycolysis and the citrate-malate shuttle, which facilitates glucose-driven mitochondrial citrate export to the cytosol