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The tirzepatide evidence base Tirzepatide's clinical record centers on the SURMOUNT program for weight management ( The New England Journal of Medicine , 2022) and SURMOUNT-OSA for obstructive sleep apnea (NEJM 2024)

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Avoid Sugary Mixers While the medication helps regulate blood sugar, sugary cocktails (like margaritas or daiquiris) can cause a spike followed by a crash

57 Similarly, inhibiting NLRP3 by suppressing Toll-like receptors (TLRs) 4 and 9 signaling pathways also results in hepatoprotection against APAP-induced liver injury

It's worth noting that Wegovy's effect of slowing gastric emptying may potentially affect the absorption of some oral medications