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The reduced form GSH is the active form of the molecule, it is the most abundant and it is found inside the cells in millimolar concentrations in the range of 110 mM (highest concentration in liver) (Figure 1) which provides its reductive power
Mashayekhi M et al
Bcl-2: B-cell lymphoma 2, Bcl-XL: B-cell lymphoma-extra large, cAMP: cyclic adenosine monophosphate, CREB: cAMP-response element-binding protein, FoxO1/O3: forkhead box transcription factor 1/3, GLP1R: glucagon-like peptide-1 receptor, GSK-3: glycogen synthase kinase-3, LTP: long-term potentiation, MAPK: mitogen-activated protein kinase, mTOR: mammalian target of rapamycin, NF-B: nuclear factor kappa B, PD: Parkinsons disease, PI3K: phosphoinositide 3-kinase, PKA: protein kinase A
About this article Cite this article Mai, Z., Wang, B., Hu, Q
Maintaining heart and bone health are key for reducing disease risk as you age
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