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Mediante la estimulacin de la liberacin de insulina y la supresin de la secrecin de glucagn (una hormona que libera el hgado y aumenta el nivel de glucosa en el torrente sanguneo), los GLP-1 contribuyen a la reduccin de los niveles de glucosa en sangre

When compared to GLP1RAs, which improve insulin sensitivity primarily through weight reduction, a post-doc regression analysis of HOMA2-IR indicates that only 2030% of the improvement in insulin sensitization observed with tirzepatide is due to weight loss (NCT03951753) [77, 78]

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