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PubMed, Hidayat, K., et al
Retatrutide is an investigational peptide medicine currently under clinical evaluation for the treatment of obesity and overweight-related conditions
Several newer classes of drugs include glucagon-like peptide-1 (GLP-1) receptor agonists and dual gastric-inhibitory peptide (GIP)/GLP-1 receptor agonists
[1] [4] For patients with type 2 diabetes and established cardiovascular disease, Ozempic is indicated to reduce cardiovascular risk, while Wegovy is approved for cardiovascular risk reduction in adults with obesity/overweight and established cardiovascular disease
This lifts the subcutaneous layer away from underlying muscle
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