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A GLP-1 agonist targets one hormone pathway, while a triple agonist activates multiple metabolic pathways simultaneously

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Not every person who might be eligible for retatrutide will need to lose weight at such a fast ratean average of nearly 37 pounds over 40 weeksand such a rapid drop in A1C is also something that ought to be watched for additional side-effects, she says

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Clinical trials show semaglutide produces 15-22% body weight reduction, while GLP-1 supplement studies report 3-5% results