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Iron uptake primarily occurs via transferrin receptor 1 (TfR1)-mediated endocytosis, where transferrin-bound iron (Fe 3+ ) is reduced to Fe 2+ by six-transmembrane epithelial antigen of the prostate 3 (STEAP3) and released into the cytosol (Kawabata, 2019)
On the second day, after three washes with PBS, cells were incubated with donkey anti-rabbit IgG (A21206, 1:100, Thermo Fisher Scientific, United States)
Panche AN, Diwan AD, Chandra SR
NTZ significantly alleviated MTX-induced oxidative stress, which can be attributed to the antioxidant properties of its structural moieties (nitrothiazole and salicylamide) (Hemphill et al., 2006
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