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SELENOP also functions as an antioxidant that protects cells from oxidative damage by enabling full activity of thioredoxin reductases and glutathione peroxidases through adequate supply of selenium to extrahepatic tissues (see Glutathione peroxidases)

Glutathione works in two ways: directly, by using its reactive cysteine thiol group to neutralize free radicals and peroxides

Additionally, this study was performed in male mice, and studies in female mice are warranted due to potential differences in the weight loss response after semaglutide/BI8271 between sexes

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