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This peptide binds to a specific receptor on the surface of beta cells in the pancreas, causing them to release insulin, and for a long time researchers assumed that GLP-1 analogues only affected insulin release, hence why they were prescribed for type 2 diabetes

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Both the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines and the American Diabetes Association (ADA) endorse multidisciplinary care coordination as a central pillar of comprehensive DKD management (167)