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The mechanistic concern voiced by dermatologists is not usually that the compound initiates melanoma from nothing, but that stimulating melanocytes may accelerate progression of pre-existing dysplastic or early-mutated lesions toward malignancy
The patch may contribute to accelerated wound healing
The percentage of transduced cells compared with the total iSPNs was similar in scrambled shRNA (16.4%) and Gsto2 -shRNA (~17.7%) injected mice
This allows tissue pressure to equalize
What to do with results: If markers improved, you have evidence the protocol worked
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