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Clinical evidence shows that discontinuing semaglutide after weight loss leads to significant weight regain (approximately 7% within one year)
B.DiasC.MagidaJ.Mazei-RobisonM.LoboM.KennedyP.et al
That may be enough to treat type 2 diabetes but not enough to provide a 15% weight loss as seen with injectable semaglutide
172 Natural compounds such as curcumin, quercetin, and salvianolic acid B have also demonstrated transporter-inhibitory properties with relatively low toxicity, although issues with solubility and bioavailability have limited their clinical utility and prompted formulation optimization
Potential risks of GLP 1 patches include skin irritation, cardiovascular effects from certain herbal ingredients, and potentially delayed access to proven treatments
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