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The approved-pathway comparison points remain tirzepatide (Mounjaro/Zepbound) on its own and the investigational CagriSema (cagrilintide + semaglutide)

The Combo Versus Other Popular Stacks The Retatrutide and Cagrilintide pairing is not the only stack people consider, so it helps to see where it sits against the alternatives Canadians most often weigh