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When evaluating semaglutide options (compounded via PlexusDx or branded Wegovy), genetic context can deepen the provider-patient discussion about likelihood of metabolic benefit, appropriate dosing escalation, and whether the peptide pathway represents the optimal therapeutic target for an individual
When to contact your healthcare provider Contact your healthcare provider right away if you have: severe or persistent side effects vomiting that does not stop severe stomach pain trouble breathing swelling of the face or throat signs of dehydration yellowing of the skin or eyes confusion or fainting vision changes References Wegovy (semaglutide) prescribing information
Cryo-EM density map and the model are shown for all seven transmembrane (TM) helices and helix 8 of GLP-1R, GLP-1(7-37), and LSN3160440 (zoomed in)
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