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287 This theoretical perspective shifts the focus from static oncogenic drivers to the dynamic stability and plasticity of the signaling network as a whole, explaining why monotherapies often fail and providing a rationale for combinatorial strategies that target network vulnerabilities
& Fishel, S
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APOE comes in four variants: APOE1 (extremely rare and not considered further), APOE2 (rare), APOE3 (most common), and APOE4 (common) (Belloy et al., 2019)
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