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We set statistical significance at two-sided p -values less than 0.05 for initial assessment, then applied Bonferroni correction across our six prespecified primary ocular outcomes (adjusted = 0.0083) to maintain appropriate family-wise error control
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If the data were parametric, a students T -test or ordinary one-way ANOVA with Holm-dk multiple comparisons test with a single pooled variance was performed
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