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The study was funded through a Novo Nordisk research grant to the Groninger Medical University Center
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Novo Nordisk may have first-mover advantage in the oral space, with oral Wegovy (obesity) and Rybelsus (T2D, launched 2019), but orforglipron is expected to outperform these on-market semaglutide options for a number of reasons: superior HbA1c reduction and weight loss
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Over the next 52 weeks, the placebo group regained an average 14.0% of body weight while the tirzepatide group lost an additional 5.5%, a 19.4 percentage-point gap
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