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Here are the steps: Ground coffee is brewed normally and cooled to body temperature

Peptides (2019) 111:2632

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X-ray crystallographic studies have demonstrated that copper coordination occurs through the N-terminal amino group of glycine, the deprotonated peptide nitrogen of the Gly-His bond, and the imidazole nitrogen of histidine, forming a square-planar geometry characteristic of Cu(II) complexes