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There is accumulating evidence for diverse changes in molecular expression of reactive astrocytes in different types and different severities of tissue pathology, 62,65,68,69 but there is not yet a good synthesis of how molecular, metabolic, 87 structural, and functional changes relate to one another to generate precisely definable phenotypes

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Western blot analysis Protein samples were extracted from mouse liver tissue lysates and Huh-7 cells

The striatum expresses high ferritin levels for the buffering of iron