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Escherichia coli, Streptococcus faecalis, Clostridium difficile and certain Salmonella species can bind Se from the body to their own enzymes to use amino acids instead of thiamine-containing amino acids, and can also convert the soluble form of Se to an insoluble form, making it unavailable for absorption by the body (114)
If you are experiencing sexual dysfunction that is bothersome as a result of your medication, there are other antidepressants that have lower rates of sexual dysfunction
Researchers care about it because it acts on three hormone pathways at once: GLP-1, GIP, and glucagon