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Less commonly used today, but still helpful in selected patients with insulin resistance and fatty liver
The situation has really improved a lot
It has protective features on the -cells survival, and this has a synergistic effect with GLP-1 in healthy humans, but this mechanism is impaired in those with T2DM [21,22]
This led to the demonstration that DPP-4 inhibitors may protect the endogenous molecule [14] and to the development of clinically useful DPP-4 inhibitors, which have found clinical use worldwide
Finally, the applicability of our findings to other tumor types necessitates further investigation
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