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conducted a randomized controlled trial in obese older adults with cardiovascular or metabolic conditions, comparing three intervention groups: caloric restriction alone (WL), caloric restriction combined with aerobic training (WL + AT), and caloric restriction combined with resistance training (WL + RT)

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This comparison illustrates the gap between novel molecular mechanism discovery and validated clinical translation Dihexa represents frontier neuroscience with unresolved questions, while Cerebrolysin represents established but less mechanistically precise neurotrophic therapy

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