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The reduction was most notable in the hippocampal CA1 area and cortex, while it was not clearly observed in other regions like CA3

But the risk column tells the story of why it should not

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Sin embargo, esta zona puede ser ms difcil de alcanzar para la autoadministracin y muchos pacientes necesitarn asistencia de un cuidador o familiar para inyectar en esta ubicacin si no pueden alcanzarla adecuadamente

Gene expression analyses showed that eight genes involved in GSH metabolism were correlated to GSH concentrations, 2 of which (gamma-glutamyltransferase 1 [GGT1] and thioredoxin reductase 3 [TXNRD3]) were also correlated to MTX resistance