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They manage pain and inflammation but do not reduce or eliminate the fibrous tissue buildup within the joint

doi:10.1046/j.1365-2362.2001.00781.x

Amino acid sequence and function of the light subunit of rat kidney -glutamylcysteine synthetase

During the lipid peroxidation pathway, ACSL4 promotes ferroptosis by producing oxidized PE at the endoplasmic reticulum (ER)-associated oxygenation center, and ACSL4 catalyzes the attachment of AA or adrenaline (AdA) to produce AA or AdA acyl Co-A derivatives, which is then esterified to PE (AA-PE and AdA-PE) by lysophosphatidylcholine acyltransferase 3 (LPCAT3)

Annu Rev Immunol (2009) 27:66992