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Intensive weight loss intervention and cancer risk in adults with type 2 diabetes: analysis of the Look AHEAD randomized clinical trial
A previous smaller open-label study had reported improvement in lean mass and marginally lower HbA1c in men treated with testosterone (fortnightly intramuscular testosterone cypionate) over 18 months [55]
About 50% achieved 15% or greater weight loss
Through its peroxidase activity, PRDX6 directly reduces PL-OOHs, providing antioxidant defense even in the absence of GPX4
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