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Key results: Average weight loss: 14.9 percent (approximately 33 pounds for a 220-pound individual) 50 percent of participants lost at least 15 percent of body weight 32 percent of participants lost at least 20 percent Significant improvements in waist circumference, blood pressure, HbA1c, and quality of life Brand Names and Availability Semaglutide is marketed as Ozempic for type 2 diabetes and Wegovy for weight loss

This is what early-cycle Loss of Exclusivity (LOE) pressure looks like: global pharma racing to secure distribution and brand loyalty for next-generation assets years ahead of their own major patent cliffs, driven by the looming generic threat to a top rival

Retatrutide's price has not been announced, as the drug has not yet received FDA approval

This cleanup is expected to save roughly 300 crore annually in interest costs , bolstering margins and profit before tax from next year onward