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Multi-agonists A single drug that acts at two or more different receptors may enhance weight loss compared with single receptor agonists and has the advantage of a single pharmacokinetic profile compared with multiple profiles observed with the co-administration of two or more drugs [38]
In contrast, endogenous antioxidant systems are a complex and compartmentalized network that involve controlled and localized production of specific ROS [54]
But theres a catch: Because these medications reduce appetite so effectively, people often: Eat much less overall Miss out on protein and fiber Lose muscle mass along with fat A recent JAMA Internal Medicine patient guide emphasizes that people on GLP-1 medications commonly lose both fat and lean mass, and may experience GI symptoms that make eating harder
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In either case, you should monitor when you experience joint and muscle pain and whether there is a correlation with your recent activity
