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Popular GLP-1 drugs like Ozempic for weight loss and Wegovy diabetes treatment have been approved for long-term use under medical supervision
Therefore, an elevation of H 2 O 2 in transgenic plants was mainly due to the decrease of CAT and POD activities and increase of SOD activity to cause the higher accumulation of MAD leading to lipid peroxidation and reduce tolerance to freezing stress
Later on, it has been shown that more than 200 variants exist in the coding region of TMAO producing enzyme, with different outcomes on the cardiovascular risk (Phillips and Shephard, 2020)
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