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Patients with a personal or family history of medullary thyroid carcinoma or MEN2 syndrome should not use tirzepatide
Final Thoughts Tirzepatide (Mounjaro/Zepbound) offers a path to significant health improvements, but the gastrointestinal side effects, particularly constipation, are a real challenge
Laura Franzese, in Portland, Ore., learned about the licensing problem after spending $1,000 on a bulk order of tirzepatide from Zappy that arrived with Ousia labels
Large injection volumes or shallow injections can also increase discomfort
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