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Several studies have identified protein arginine methyltransferase (PRMT) 1, PRMT4, PRMT5, and PRMT7 as key regulators of fibroblast activation and differentiation in fibrosis
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A chimeric Sm multi-epitope (Sm14, Sm21.7, Sm23, Sm29, Smp80, Smcb, and Sm-tsp-2), subunit vaccine formulated with a novel TLR4 agonist induced humoral and cellular immune responses suggestive of its potential as a prophylactic or therapeutic vaccine (71)
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