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The slow titration can help with the tolerability as nausea is a common class adverse effect

In a 96-well plate, the adduct solution was treated with the appropriate amount of an aqueous stock solution of GSH, GSSG, cysteine, H 2 S or taurine, and the solutions were incubated at 20 C for 3060 min

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Therefore, the heterogeneities in cardiovascular medication, baseline characteristics, study population, and study design should be taken into consideration when comparing the results among these trials