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However, GLP-1 receptor agonists are not recommended if you: - Are pregnant - Are hypersensitive to GLP-1 - Have severe gastrointestinal conditions like inflammatory bowel disease (IBD) - Are at a higher risk of certain thyroid cancers If you have a history of pancreatitis, kidney failure, or gallbladder disease, GLP-1 receptor agonists may not be safe for you
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Oxyntomodulin Activates Both GLP-1 and Glucagon Receptors Controlling Energy Balance and Glycaemia Given OXM contains the entire glucagon sequence, it is no surprise that this peptide activates the glucagon receptor (13, 33)
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