Heruye, S.H., Nkenyi, L.N.M., Singh, N.U., Yalzadeh, D., Ngele, K.K., Njie-Mbye, Y., Ohia, S.E., and Opere, C.A., Current Trends in the Pharmacotherapy of Cataracts
Methionine is an essential amino acid, and selenium is an antioxidant that acts as a cofactor for glutathione peroxidase which neutralizes hydrogen peroxide (see Figure 1)
These amino acids are ultimately obtained from our food or over-the-counter supplements
Its primary mechanism involves binding to MC1R receptors in melanocytes, triggering increased production of eumelaninthe pigment responsible for darker skin tones
Starting conservative rather than titrating up aggressively is the single biggest lever you have over how noticeable this side effect gets