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Adverse event reports Between February 2019 and December 2023, the FDA received 352 adverse event reports related to compounded GLP-1 drugs
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Tirzepatide (Mounjaro) and Semaglutide (Ozempic, Wegovy) both help with blood sugar control and weight loss, but Tirzepatide has a dual-action mechanism that targets both GLP-1 and GIP receptors, while Semaglutide only targets GLP-1
The long half-life creates a relatively smooth concentration curve throughout the week
For this reason, during the phases with a predominant Th2 response, greater immunosuppression can appear, causing outbreaks of viral reactivation as occurs, for example, with the herpes simplex virus type 1, which in these phases usually causes vesicles to appear on the lips [217]
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