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This is particularly valuable for patients who need a slower titration schedule due to side effects, patients who require a dose between the available brand increments, or patients for whom the standard titration pace produces intolerable gastrointestinal symptoms

About GLP-1/GIP Brands: The difference between Mounjaro & Zepbound Mounjaro and Zepbound are injectable treatments that include both GLP-1 and GIP hormones, designed to work together in reducing appetite and supporting weight loss

That delivery technology is independently patentedmeaning a generic manufacturer would need to either replicate it or develop an alternative approach that achieves the same result, adding another layer of complexity on top of the molecule itself

To minimise discomfort, healthcare professionals recommend gradual dose escalation, also known as titration, which allows the body to adjust to the medication in a stepwise manner

A prospective cohort study compared the effect of metformin as monotherapy versus metformin with additional therapy of either insulin or GLP-1 RA on lung function in 32 non-asthmatic patients with T2D over 2 years [99]