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1 However, it is recommended to avoid use in patients with a personal or family history of MTC and in patients with multiple neoplasia syndrome type 2

Importantly, these criteria intentionally exclude peptide systems for which multiple well-designed human studies have demonstrated a lack of efficacy or unacceptable safety profiles

Discontinue use and contact your healthcare provider if you experience any adverse reactions

Supports cognitive health: Emerging research suggests creatine may benefit brain function by enhancing ATP availability in brain cells, potentially improving memory and mental stamina

Everything needs to be in balance.[ref][ref] Prostate cancer risk is increased with 4-HOE1(E2) metabolites also.[ref] In general, the estrogen metabolites that start with 2 are good, and the ones that start with 4 or 16 need to be limited or at least eliminated quickly from the body.[ref] Here is a diagram of how these metabolites go together: As you can see, upregulating the CYP1A1 enzyme is going to increase the 2-OHE1 path