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Consistent with the ion-centric model above, HIV-1 Tat can upregulate NLRP3, promote ASC oligomerization and caspase-1 activation, and augment IL-1 release by inhibiting miR-223, thereby contributing to microglial activation [101] (Fig

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Effects of intracerebroventricular injection of delta sleep-inducing peptide (DSIP) and an analogue on sleep and brain temperature in rats at night

Typical b12 deficiency symptoms include persistent fatigue, breathlessness, glossitis and pallor