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10.3389/fimmu.2019.02655 448 ValeriF.Dos Santos GuilhermeM.HeF.StoyeN
In contrast, serine-induced mTOR inhibits Tregs suppressive activity (impeding Foxp3 expression), but this can be reversed by serine degradation to glutathione [110], reinforcing that the manner by which cells metabolize some amino acids can influence their function, being a target for therapies
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Potential tumor promotion : Given its angiogenic properties, there is theoretical concern it could contribute to tumor growth or neovascularization in certain contexts
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