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What cardiovascular benefits are due to the drug itself versus the weight loss
Clinical studies show different weight loss outcomes depending on whether semaglutide is used for diabetes (Ozempic) or weight management (Wegovy)
For weight management candidates, comprehensive evaluation should include assessment of previous weight loss attempts, evaluation for secondary causes of obesity (hypothyroidism, Cushing's syndrome, medication-induced weight gain), screening for eating disorders, and discussion of realistic expectations and long-term commitment to therapy
Short-acting GLP-1 analogs (Table 2) reduce glucose response after eating food by increasing insulin secretion and delaying gastric emptying
The key is the medical necessity established by your clinical consultation
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