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These individuals generally tolerate coffee well and usually do not have sleep issues even when drinking it in the afternoon

However, individuals should consult healthcare providers before use, particularly if they have underlying conditions or take other medications, Dr

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In the Phase 2 obesity trial it produced about 24% weight loss at 12 mg over 48 weeks, the most of any drug in the class, and it cut liver fat by 86% in the people who started with fatty liver. In the 80-week Phase 3 obesity trial of 2,300 adults with an average BMI of 40, 12 mg produced 28% weight loss and 9 mg reached 26%

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