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Causes of Melasma: Hormonal fluctuations (pregnancy, birth control pills, hormone therapy) UV radiation exposure Genetic predisposition Heat and infrared light Appearance of Melasma: Symmetrical patches on the cheeks, forehead, nose bridge, or upper lip Larger, diffused patches rather than sharp dark spots Worsens with sun exposure What is Post-Inflammatory Hyperpigmentation (PIH)

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L-methionine toxicity in freshly isolated mouse hepatocytes is gender-dependent and mediated in part by transamination

doi: 10.1016/j.jad.2019.11.122CrossRefGoogle ScholarPubMed Bersani, G., Meco, G., Denaro, A., Liberati, D., Colletti, C., Nicolai, R., Koverech, A

Do not exceed the recommended daily intake unless otherwise directed by a healthcare professional