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We present the strategy of utilizing small molecule analogs specifically designed to penetrate the blood-brain barrier and facilitate dimerization and activation of the HGF/Met receptor system
doi:10.1089/acm.2011.0503, PMID: 22757691 Ding W, Liu Y (2011) Genistein attenuates genioglossus muscle fatigue under chronic intermittent hypoxia by down-regulation of oxidative stress level and up-regulation of antioxidant enzyme activity through ERK1/2 signaling pathway
Cell Rep (2019) 29:273144 e4
In addition, PAC has the capacity to reduce fever and pain as well as NSAIDs (Messika et al., 2014), and may equally mask the symptoms delaying the objective grading of the disease, but it lacks the NSAIDs anti-inflammatory and antiplatelet activities that might be fundamental in containing COVID-19 exacerbation (Giardini et al., 2020)
A., Gonzalez-Cantu, J
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