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& MacFabe, D

Column and autosampler were kept at 40 C and 4 C, respectively

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Particular emphasis is placed on the key technologies enabling the transition from chemical synthesis to scalable biomanufacturing, including tandem-repeat expression, high-cell-density fermentation, inclusion-body-assisted purification, and Cu(II) complex stabilization

This was associated with an increase in bile acid synthesis pathways and a trend towards greater cholangiocyte signature (Figure 1) in BA1 compared to BA2